These studies were published as abstracts and were presented at a convention. These data and conclusions should be considered to be preliminary until published in a peer reviewed journal.
Despite other recent reports, this handful of little studies suggest that e-cigarettes could be associated with adverse lung function immediately when they’re smoked.
BARCELONA — Persons who smoke e-cigarettes seem to possess decreased in lung function and other adverse health effects irrespective of tobacco-smoking history, investigators said here.
“Our study proves that even a single usage of an e-cigarette raised pulse and symptoms like cough and sore throat,” Vakali stated. “Claims that electronic cigarettes can help smokers quit need to be backed-up by clinical studies and toxicity analyses and function within the proper regulatory framework.”
The researchers recruited 16 smokers with COPD, 12 smokers with asthma, 29 smokers with no 11 nonsmokers and symptoms and then asked about different symptoms in addition to their satisfaction factor.
Following e-cigarette use, sore throat was experienced by 74% of the nonsmokers; 65% of smokers; 91% of asthmatics and 62% of people with COPD.
Cough was experienced by 69% of smokers, 54% of non-smokers, 66% of asthmatic smokers, and 69% of individuals with COPD.
Other symptoms noted by all participants included dry mouth and eye irritation.
Regardless of the adverse events, 51% of smokers and 18% of the non smokers said they did get joy from smoking the e-cigarettes. One in four asthmatics and 44% of those with COPD also mentioned the e-cigarette supplied a wonderful experience.
Vakali also found that oxygen saturation was reduced among those smoking the e-cigarettes, reaching a significant decrease among smokers (P>0.001).
In a second paper, Vakali split subjects into those smoking an e-cigarette free of nicotine and a second team that smoked e-cigarettes laced with 11 mg of nicotine.
“An increase in exhaled carbon monoxide was detected in most subjects,” she said. “Increased heart-rate and palpitations are related to using a nicotine containing e-cigarettes but airway signs such as sore throat and cough and other inflammatory markers are independent of nicotine use.”
In a third study from the Athens team, Georgios Kaltsakas, MD, a physician in the hospital, discovered that smoking e-cigarettes raised airway resistance and reduced special airway conductance.
“This is not good,” he said. “Nonsmokers began with resistance which is normal, but smokers had above normal resistance.” He illustrated that smoking e-cigarettes raised that resistance “even after 10 minutes of smoking e-cigarettes.
He assessed lung function before and after smoking e-cigarettes. A significant increase in airway resistance was shown in smokers (P=0.033) and in never smokers (P=0.006), he told MedPage Today. These teams also showed declines in specific airway conductance.
Christina Georgia Gratziou, MD, professor of pulmonary medicine at the University of Athens, who directed the research team, cautioned that the findings were preliminary.
“Our studies suggest that e-cigarettes could cause impairment in lung function,” she told MedPage Today. “We must do more studies and we should extend the study within our citizenry.
“But certainly there are a few indications you need to be careful. We want regulations for these e-cigarettes,” she said.
In commenting on the e-cigarette use, Christopher Bullen, MBchB, Ph.D., MPH, director of the National Institute for Health Innovation, Auckland, NZ, told MedPage Today “There have been concerns about lung function with e-cigarettes. People are involved when you are going to inhale something deep in your lungs which these issues purport to do they could they be creating some type of adverse effects on lung function or with longterm use could that cause problems such as cancer.
“The jury is still out on that,” Bullen stated. “Some studies have shown that there are modest changes in lung function that is similar to what you see with cigarettes.
“Still, I think it is very likely that e-cigarettes are a lot better than actually smoking tobacco. At this stage the e-cigarettes are much less dangerous,” he said